Phenelzine (Nardil)

You should not use phenelzine if you are allergic to it, or if you have:

• pheochromocytoma (tumor of the adrenal gland).
• congestive heart failure;
• severe kidney disease; or
• a history of liver problems or abnormal liver function tests.

A dangerous drug interaction can occur between phenelzine and certain other medicines you use within 14 days before or after taking phenelzine. Your doctor may change your treatment plan if you need to use any of these medicines, including:

• epinephrine or norepinephrine;
• bupropion, buspirone, carbamazepine, guanethidine, levodopa, meperidine, methyldopa, tryptophan;
• ADHD medication;
• diet pills, cough and cold or allergy medicines;
• opioid medicine;
• other antidepressants;
• another MAO inhibitor--furazolidone, isocarboxazid, linezolid, methylene blue injection, procarbazine, rasagiline, selegiline, tranylcypromine, and others; or
• drugs that affect serotonin levels in your body--stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting.

This is not a complete list and there may be other medicines you should not take while you are taking phenelzine.

Tell your doctor if you have ever had:

• high blood pressure, heart disease;
• diabetes;
• schizophrenia;
• epilepsy or other seizure disorder; or
• if you have taken another antidepressant within the past 5 weeks.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Phenelzine is not approved for use by anyone younger than 18 years old.