Lubiprostone (Oral)
Lubiprostone is used to treat chronic constipation, or constipation caused by opioid pain medicine.
Lubiprostone may also be used to treat irritable bowel syndrome in women with constipation as the main symptom.
Lubiprostone may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Lubiprostone (Oral)?
You should not use lubiprostone if you have a blockage in your digestive tract, or if you have severe diarrhea.
Tell your doctor if you have ever had liver disease.
Tell your doctor if you are pregnant or breastfeeding.
If you are breastfeeding, tell your doctor if you notice diarrhea in the nursing baby.
Not approved for use by anyone younger than 18 years old.
Side Effects
What are the side effects of Lubiprostone (Oral)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe or ongoing nausea or diarrhea;
- trouble breathing; or
- a light-headed feeling, like you might pass out.
You may have low blood pressure and feel faint shortly after taking lubiprostone, especially if you've been sick with vomiting or diarrhea. Stop taking lubiprostone and call your doctor if you feel light-headed after every dose or if you have severe diarrhea.
Common side effects may include:
- nausea, stomach pain;
- diarrhea, gas, bloating; or
- headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Lubiprostone (Oral) if I’m pregnant or breastfeeding?
Tell your doctor if you are pregnant or breastfeeding.
If you are breastfeeding, tell your doctor if you notice diarrhea in the nursing baby.
Interactions
What drugs and food should I avoid while taking Lubiprostone (Oral)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Lubiprostone (Oral)?
Use Lubiprostone (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take with food and water.
Swallow the capsule whole and do not crush, chew, break, or open it.
You may have tightness in your chest or feel short of breath within 1 hour after taking lubiprostone. This side effect should go away within 3 hours, but it may occur again when you take your next dose. Talk with your doctor if this side effect becomes bothersome.
Do not take lubiprostone if you have severe diarrhea. Call your doctor for instructions.
Your doctor will need to check your progress on a regular basis.
Store at room temperature away from heat and light.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Overdose Signs
What happens if I overdose on Lubiprostone (Oral)?
Images
SPI
Color: pink
Shape: oval
Form: gel coated
Imprint: SPI
SPI
Color: orange
Shape: oval
Form: gel coated
Imprint: SPI
24 mcg, SPI
Color: orange
Shape: capsule
Imprint: 24 mcg, SPI