How Stress Can Trigger Eczema, and How to Avoid a Flare-Up

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Strategies like mindfulness meditation can help reduce stress-related eczema flares.Oscar Wong/Getty Images

The symptoms of eczema — which can include very dry or itchy skin that may crack and ooze clear liquid when scratched — are not constant.

Rather, symptoms vacillate from worse to better to worse again, often thanks to specific triggers that activate inflammation.

“There are many potential triggers for eczema, and each individual may have specific triggers for their own symptoms,” says Peter Lio, MD, a dermatologist at Northwestern University’s Feinberg School of Medicine in Chicago.

Triggers of eczema, which is also called atopic dermatitis, include things like:

  • Overly dry skin
  • Dry, cold climate, particularly during winter
  • Sweat
  • Irritants such as metals, cigarette smoke, fragrances, and fabrics like wool and polyester
  • Allergens, such as mold, pollen, dust mites, and pet dander
  • Various foods that cause allergic reactions, such as eggs, soy, shellfish, tree nuts, peanuts, fish, wheat, and milk
  • Bacterial, viral, and fungal infections
  • Hormonal changes, particularly during pregnancy or in the days before menstruation

Stress is another common trigger for eczema symptoms.

For some people, various external factors, such as school or work, can cause stress, resulting in worsening eczema symptoms. For others, flare-ups result from the stress of knowing they have eczema. The psychological stress of having eczema can often lead to more significant problems.

Eczema and Other Mental Health Issues

In a 2016 survey by the National Eczema Association, about one-half of the respondents said they were bothered by poor sleep and symptoms of mental health issues like depression and anxiety caused by eczema. The skin condition also affected their ability to effectively engage in self-improvement activities.

A study published in 2020 looked at medical records of more than 500,000 adults with atopic eczema and more than 2.5 million without the skin condition in the United Kingdom over 18 years. The results revealed that individuals with eczema had a 14 percent greater risk of developing depression and a 12 percent increased risk of anxiety than those without eczema. Furthermore, those with severe eczema were even more likely to develop depression — a 26 percent higher risk than those without the skin condition.

During inflammatory eczema responses, the body — particularly the skin, the body’s largest organ — communicates with the brain through various sensations, such as pain, heat, itch, and discomfort.

Controlling eczema flares induced by psychological stress may relieve symptoms of anxiety and depression and improve emotional well-being.

How Does Stress Worsen Eczema Symptoms?

The link between psychological stress and eczema is multifaceted, though the connection appears to stem from stress hormones.

“Stress is a very common trigger for both children and adults,” Dr. Lio says. While there are many theories about how stress and eczema are connected, researchers have found that there is a network in the body that both directly and indirectly affects the immune system, the skin barrier, and behavioral aspects of eczema, he explains.

“One of the hardest parts is that there can be a vicious cycle: The skin and symptoms cause more stress, which then, in turn, worsens the skin,” Lio says.

When we experience stress, the body undergoes a “flight or fight response,” also known simply as the stress response.

Part of this response is the activation of the so-called HPA axis, a network involving the hypothalamus, pituitary gland, and adrenal glands, which produce hormones.

The HPA axis increases the amount of cortisol — a stress hormone — circulating in the body.

Cortisol is an immune system regulator and ultimately causes an imbalance in the body’s different types of immune responses, resulting in the increase of cell signaling molecules that promote inflammation.

Part of this cascading response from the immune system imbalance is an increase in the production of immunoglobulin E (IgE) antibodies, which cause allergic reactions.

The body also experiences various other physiological changes that affect the skin.

For example, the production of mast cells increases — these white blood cells release histamine, a compound that causes itchiness. Stress also causes our blood vessels to dilate, which leads to a further release of histamine. Additionally, sensory nerves release molecules that can disrupt the normal functions of the outermost layer of the skin (the skin barrier).

These and other responses work in concert during stressful events and drive up eczema symptoms.

Mindful Meditation and Relaxation Practices for Stress

Research suggests that mindful meditation — especially regimens like mindfulness-based stress reduction (MBSR) — can help alleviate psychological stress and improve emotional well-being.

In a review published in 2014, researchers found that mindfulness meditation programs can help reduce anxiety, depression, and pain.

More recently, a study from 2017 showed that MBSR reduced stress hormones and inflammatory molecules in people with generalized anxiety disorder, suggesting the practice helped people better deal with stress and may reduce inflammation.

Mindfulness meditation involves sitting comfortably; focusing on deep, steady breathing; and paying close attention to the present moment, particularly your own thoughts, emotions, and sensations.

Other complementary relaxation techniques include:

  • Light, graceful exercises, such as yoga, tai chi, or ballet
  • Positive imagery or visualization, in which you focus your thoughts on an image associated with your desired change, such as a tropical rain forest to represent moist skin

  • Acupuncture, a traditional Chinese medicine in which thin needles are inserted at specific points of the body
  • Distraction activities, such as writing, painting, video games, and knitting
  • Listening to soothing music or nature sounds

Lio says he typically introduces his patients to several of these techniques and asks which ones sound good to them. “Finding ways to relax and destress is critical,” he says. “Sometimes it takes a few tries to find the right fit for someone, but once found, it can make a tremendous impact.”

The Importance of Exercise for Stress Relief

The U.S. Department of Health and Human Services recommends that adults living with a chronic condition get between 150 and 300 minutes of moderate-intensity exercise, such as walking briskly, biking lightly, raking your yard, or mowing the lawn.

Alternatively, you could also meet your exercise requirement by getting 75 to 150 minutes of vigorous-intensity (or a combination of moderate- and vigorous-intensity) aerobic exercise each week. Vigorous-intensity exercise includes running, hiking, playing soccer, or playing tennis singles.

In addition, the department advises adults practice strength training that activates a variety of muscles two times per week. These activities can also deepen breathing and relieve muscle tension. Just be sure to get clearance from your doctor before beginning a new exercise routine.

If sweat is a flare-up trigger for you, make sure to take a shower after exercising and change your clothes. Wear light, breathable fabrics while working out that don’t rub or scratch the skin. Drink plenty of water before, during, and after exercise to stay hydrated and take breaks during your workout if you sense an eczema flare coming on.

Sleeping Well When You Have Eczema

The itchy, uncomfortable skin associated with eczema can make sleeping difficult.

Lack of sleep can cause stress and worsen eczema symptoms, especially if sleeplessness occurs the night before an important activity or tiredness interferes with important activities during the day.

What’s more, research has shown that sleep loss, even if it occurs for just one night, can increase inflammation.

According to the National Eczema Association, these tips will help you get a better night’s sleep:

  • Wake up and go to bed at the same time every day.
  • Create a consistent, relaxing bedtime routine.
  • Stop using electronics 30-60 minutes before bedtime.
  • Limit caffeine intake after lunch.
  • Keep your bedroom dark, cool, and comfortable. 

Better Support to Cope With the Stress of Eczema

Positive social relationships are important for physical and mental well-being.

A study from 2016 suggested that social networks are just as important as diet and exercise throughout your whole life.

Social isolation in adolescence, for instance, increases the risk of inflammation.
If you don’t have a strong group of friends or family that regularly provide emotional support, find an eczema support group.

Additional reporting by Ashley Welch.

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