Glucagon (Glucagen)

Glucagon is a hormone that increases blood sugar levels. It also slows involuntary muscle movements of the stomach and intestines that aid in digestion.

Glucagon is used to treat hypoglycemia (low blood sugar). Glucagon is also used during a radiologic (x-ray) examination to help diagnose certain disorders of the stomach or intestines.

Glucagon may also be used for purposes not listed in this medication guide.

uses

What is Glucagon (Glucagen) used for?

warnings

What is the most important information I should know about Glucagon (Glucagen)?

You should not use this medicine if you are allergic to glucagon or lactose, or if you have:

  • a tumor of the pancreas (insulinoma); or
  • a tumor of the adrenal gland (pheochromocytoma).

Glucagon should be used to treat hypoglycemia only if the person is unable to eat, or is unconscious or having a seizure.

Tell your doctor if:

  • you have any tumor of the pancreas;
  • you have not recently eaten on a regular basis; or
  • you have chronic low blood sugar.

Do not give this medicine to a child without medical advice.

Glucagon is not expected to harm an unborn baby, but quickly treating hypoglycemia would outweigh any risks posed by using glucagon.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.

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Overall rating for Glucagon (Glucagen)

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Side Effects

What are the side effects of Glucagon (Glucagen)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; fast or slow heartbeat; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of the following skin changes on your face, legs, groin, or genital area:

  • redness;
  • itching;
  • blistering;
  • crusting, scaling; or
  • other skin sores or lesions.

Common side effects may include:

  • nausea, vomiting; or
  • swelling where an injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Glucagon (Glucagen) if I’m pregnant or breastfeeding?

B
No evidence of risk in humans
Based on FDA pregnancy categories

Glucagon is not expected to harm an unborn baby, but quickly treating hypoglycemia would outweigh any risks posed by using glucagon.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.

Interactions

What drugs and food should I avoid while taking Glucagon (Glucagen)?

Avoid drinking alcohol. It can lower your blood sugar.

Dosage Guidelines & Tips

How to take Glucagon (Glucagen)?

Use Glucagon (Glucagen) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Hypoglycemia should be treated as quickly as possible. Having low blood sugar for too long can cause seizure, coma, or death.

Glucagon is injected under the skin, into a muscle, or into a vein. You will be shown how to use emergency glucagon injections for severe hypoglycemia. Call your doctor after each time you use a glucagon injection.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Be sure you know how to give a glucagon injection before you need to use it. The correct dose for a child is lower than an adult dose. A child's dose may also be based on how much the child weighs. Follow your doctor's dosing instructions very carefully.

You may need to mix glucagon with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

After the injection, you should eat a fast-acting source of sugar (fruit juice, glucose gel, hard candy, raisins, or non-diet soda) and then eat a snack or small meal such as cheese and crackers or a meat sandwich.

If you are a caregiver, get emergency medical help after giving a glucagon injection. If the patient does not improve within 15 minutes, you may need to mix a new dose and give a second injection.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

To keep from having severe hypoglycemia, follow your diet, medication, and exercise routines very closely.

Store glucagon and any diluent at room temperature, away from moisture, heat, and light. Do not refrigerate or freeze. Throw away any mixed medicine you have not used right away. Do not use this medicine after the expiration date on the label has passed.

Store the auto-injector or prefilled syringe in the foil pouch and use the medicine right away after opening.

What should I do if I missed a dose of Glucagon (Glucagen)?

Since glucagon is used as needed, it does not have a daily dosing schedule.

Call your doctor promptly if symptoms do not improve after using glucagon.

Overdose Signs

What happens if I overdose on Glucagon (Glucagen)?

Overdose symptoms may include nausea, vomiting, diarrhea, rapid pulse, or high blood pressure (severe headache, blurred vision, pounding in your neck or ears).

If you think you or someone else may have overdosed on: Glucagon (Glucagen),  call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after taking Glucagon (Glucagen), call 911
911

Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.