warnings

What is the most important information I should know about Geodon (Ziprasidone (Oral/Injection))?

You should not use this medicine if you are allergic to ziprasidone, or if you have:

a heart rhythm disorder;
long QT syndrome (in you or a family member);
uncontrolled or untreated heart failure; or
if you have recently had a heart attack.

Ziprasidone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines. Your doctor may change your treatment plan if you also use:

an antidepressant;
bronchodilator asthma medication;
cancer medicine;
certain medicines for infections;
heart or blood pressure medication;
medicine to treat or prevent malaria;
medicine to prevent nausea or vomiting;
medicine to treat a psychiatric disorder; or
medicine to treat HIV or AIDS.

Ziprasidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

Tell your doctor if you have ever had:

any heart problems;
a heart attack or stroke;
fainting spells;
breast cancer;
low blood levels of potassium or magnesium;
diabetes (ziprasidone may raise your blood sugar);
seizures or epilepsy;
suicidal thoughts;
Alzheimer's disease;
trouble swallowing;
liver disease; or
kidney disease.

Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking ziprasidone without your doctor's advice.

You should not breastfeed while using this medicine.

Older adults may be more sensitive to the effects of this medicine.

Ziprasidone is not approved for use by anyone younger than 18 years old.

Side Effects

What are the side effects of Geodon (Ziprasidone (Oral/Injection))?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Stop using ziprasidone and call your doctor at once if you have:

fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
any skin rash, no matter how mild;
low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing;
high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, agitation.

Common side effects may include:

dizziness, drowsiness, weakness;
headache;
nausea, vomiting;
trouble swallowing;
weight gain;
feeling restless or being unable to sit still;
tremors, involuntary muscle movements;
vision problems; or
runny nose, new or worsening cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Interactions

What drugs and food should I avoid while taking Geodon (Ziprasidone (Oral/Injection))?

While you are taking ziprasidone, you may be more sensitive to extreme temperatures, such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking ziprasidone.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Avoid drinking alcohol. Dangerous side effects could occur.

Dosage Guidelines & Tips

How to take Geodon (Ziprasidone (Oral/Injection))?

Use Geodon (Ziprasidone (Oral/Injection)) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Ziprasidone oral is taken by mouth.

Ziprasidone injection is injected into a muscle. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.

Take this medicine with food. Swallow the capsule whole.

You may need frequent medical tests.

If you are diabetic, check your blood sugar levels on a regular basis while you are taking ziprasidone.

It may take several weeks before your symptoms improve. Do not stop using ziprasidone suddenly, even if you feel fine. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture, light, and heat.

What should I do if I missed a dose of Geodon (Ziprasidone (Oral/Injection))?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely.