Abrocitinib (Oral)

Abrocitinib (Oral)

Brand Names:Cibinqo

Abrocitinib is used in adults to treat moderate-to-severe eczema (atopic dermatitis) that did not respond to other treatments and is not well controlled with other medicines or in adults who cannot tolerate other treatments.

Abrocitinib may also be used for purposes not listed in this medication guide.

uses

What is Abrocitinib (Oral) used for?

warnings

What is the most important information I should know about Abrocitinib (Oral)?

You should not use abrocitinib with other medicines that prevent blood clots during the first 3 months of treatment. You can take aspirin (up to a dose of 81 mg each day) during this time if prescribed by your doctor.

Tell your doctor if you:

  • have an infection;
  • are a current or past smoker;
  • have had a stroke, a heart attack, or other heart problems;
  • have kidney or liver problems;
  • have low platelet or white blood cell counts;
  • have eye problems, such as cataracts or retinal detachment; or
  • have recently received or are scheduled to receive a vaccine.

Tell your doctor if you've had or been exposed to tuberculosis, or if you recently traveled. Some infections are more common in certain parts of the world, and you may have been exposed during travel.

It is not known if abrocitinib will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of abrocitinib on the baby.

It may be harder for you to get pregnant while you are using this medicine.

Ask a doctor if it is safe to breastfeed while using this medicine.

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Side Effects

What are the side effects of Abrocitinib (Oral)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening eye problems, eye pain, or changes in your vision;
  • signs of an infection--fever, sweating, or chills, muscle aches, cough or shortness of breath, weight loss, painful skin or sores on your body, diarrhea or stomach pain, burning when you urinate or urinating more often than usual, feeling very tired;
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • signs of a blood clot--sudden numbness or weakness on one side of the body, chest pain, problems with vision or speech, pain or swelling in one leg;
  • signs of a stroke--sudden numbness or weakness, severe headache, slurred speech, problems with vision or balance; or
  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects may include:

  • flu-like symptoms, tingly or painful blistering rash on one side of your body;
  • abnormal lab results;
  • pain and burning when you urinate, painful urination;
  • nausea, vomiting, stomach pain;
  • mouth and throat pain;
  • skin infection, rash;
  • cold sores;
  • high blood pressure;
  • pimples;
  • headache;
  • dizziness; or
  • tiredness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Abrocitinib (Oral) if I’m pregnant or breastfeeding?

It is not known if abrocitinib will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of abrocitinib on the baby.

It may be harder for you to get pregnant while you are using this medicine.

Ask a doctor if it is safe to breastfeed while using this medicine.

Interactions

What drugs and food should I avoid while taking Abrocitinib (Oral)?

Avoid receiving a "live" vaccine while you are being treated with abrocitinib.

Abrocitinib could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Dosage Guidelines & Tips

How to take Abrocitinib (Oral)?

Use Abrocitinib (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You should not start taking abrocitinib if you have any kind of infection unless your doctor tells you to.

Take the medicine once a day, at the same time each day.

You may take abrocitinib with or without food.

Swallow the tablet whole with water and do not crush, chew, or break it.

Your doctor should perform blood tests before you start taking abrocitinib and during treatment with this medicine.

Abrocitinib may increase your risk of certain cancers, such as lymphoma, lung cancer, and skin cancer. Ask your doctor about your risk.

Store in the original package at room temperature away from moisture and heat.

What should I do if I missed a dose of Abrocitinib (Oral)?

Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 12 hours. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Abrocitinib (Oral)?

If you think you or someone else may have overdosed on: Abrocitinib (Oral),  call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after taking Abrocitinib (Oral), call 911
911

Images

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PFE, ABR 200

Color: pink

Shape: oval

Form: film coated

Imprint: PFE, ABR 200

No image available

PFE, ABR 50

Color: pink

Shape: oval

Form: film coated

Imprint: PFE, ABR 50

No image available

PFE, ABR 100

Color: pink

Shape: round

Form: film coated

Imprint: PFE, ABR 100

Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.